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Effects of Tart Cherry Juice on the Body

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EstatiKonplete
Patwone
University of Delaware

Mo kle

Abstrè

Tart cherries are a rich source of antioxidants. Studies have shown that tart cherries exert anti-oxidative and anti-inflammatory properties. The purpose of this study is to learn about the effects of drinking tart cherry juice on cardiovascular and cognitive health.

Deskripsyon

Thirty-seven older adults were randomly assigned to drink 16 oz per day of either tart cherry juice or placebo drink for 12 weeks. Blood and urine samples were collected at baseline and 12 weeks to assess biomarkers. Physical activity and 3-day diet records were also collected throughout the study.

Dat

Dènye verifye: 09/30/2016
Premye Soumèt: 09/19/2016
Enskripsyon Estimasyon Soumèt: 10/02/2016
Premye afiche: 10/03/2016
Dènye Mizajou Soumèt: 10/02/2016
Dènye Mizajou afiche: 10/03/2016
Dat aktyèl kòmanse etid la: 10/31/2014
Dat Estimasyon Prensipal Estimasyon an: 04/30/2016
Dat estime fini etid la: 08/31/2016

Kondisyon oswa maladi

Cardiovascular Risk Factors
Age-Related Cognitive Decline

Entèvansyon / tretman

Other: Tart cherry juice

Other: Placebo juice

Faz

-

Gwoup bra

BraEntèvansyon / tretman
Experimental: Tart cherry juice
Participants consumed 16 fl. oz of tart cherry juice daily for 12 weeks.
Other: Tart cherry juice
16 fl. oz of tart cherry juice
Placebo Comparator: Placebo juice
Participants consumed 16 fl. oz of placebo daily for 12 weeks.
Other: Placebo juice
16 fl. oz of placebo

Kritè kalifikasyon yo

Laj ki kalifye pou etid 65 Years Pou 65 Years
Sèks ki kalifye pou etidAll
Aksepte Volontè HealthyWi
Kritè

Inclusion Criteria:

• Age 65-80

Exclusion Criteria:

- Allergic to tart cherries

- Heavy smoker

- Taking medications that affect cognitive function

- History of neurological disorders

- History of traumatic brain injury

- History of stroke

- Clinical diagnosis of diabetes

- Clinical diagnosis of Alzheimer's Disease/Dementia

- GI disease

- Kidney disease

- Liver disease

- Cancer

Rezilta

Mezi Rezilta Prensipal yo

1. Cognitive function [Baseline and 12 weeks]

Change from baseline in cognitive test performance at 12 weeks

Mezi Rezilta Segondè

1. Cardiovascular risk factors [Baseline and 12 weeks]

Fasting blood samples were collected at baseline and 12 weeks. Change from baseline in cardiovascular risk factors including blood lipid profiles, atherogenic risk ratios, blood glucose, hemoglobin A1c, insulin, and blood pressure at 12 weeks.

2. Oxidative stress markers [Baseline and 12 weeks]

Fasting blood samples were collected at baseline and 12 weeks. Change from baseline in plasma 8-oxoguanine (ng/ml), plasma 8-hydroxy-2deoxy-guanosine (ng/mL), plasma hydroxynonenal (ng/ml), and plasma malondialdehyde (pmole/L) at 12 weeks.

3. Inflammatory markers [Baseline and 12 weeks]

Fasting blood samples were collected at baseline and 12 weeks. Change from baseline in plasma tumor-necrosis factor-α (pg/mL) and plasma high-sensitivity C-reactive protein (ng/mL) at 12 weeks.

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