Nutritional Markers in Normal and Hyperemesis Pregnancies
Mo kle
Abstrè
Deskripsyon
Women affected with hyperemesis gravidarum are at severe nutritional risk. Reference values for biochemical parameters evaluating nutritional status during early pregnancy needs to be determined.
The investigators will compare clinical nutritional parameters (weight gain/weight loss) with rate of nausea (PUQE-questionnaire), self-reported nutritional intake form and biochemical measurements (prealbumin) in women admitted to hospital with hyperemesis gravidarum and healthy pregnant women.
For hyperemesis patients measurements will be repeated at discharge.
Dat
| Dènye verifye: | 09/30/2016 |
| Premye Soumèt: | 09/08/2015 |
| Enskripsyon Estimasyon Soumèt: | 11/29/2015 |
| Premye afiche: | 12/01/2015 |
| Dènye Mizajou Soumèt: | 10/03/2016 |
| Dènye Mizajou afiche: | 10/04/2016 |
| Dat aktyèl kòmanse etid la: | 08/31/2015 |
| Dat Estimasyon Prensipal Estimasyon an: | 04/30/2017 |
| Dat estime fini etid la: | 06/30/2018 |
Kondisyon oswa maladi
Entèvansyon / tretman
Other: PUQE-form inclusion
Other: Nutritional form inclusion
Other: Blood sampling inclusion
Other: Hyperemesis gravidarum
Faz
Gwoup bra
| Bra | Entèvansyon / tretman |
|---|---|
| Hyperemesis gravidarum Hyperemesis gravidarum patients admitted to hospital PUQE-form inclusion (PUQE-score), Nutritional form inclusion, Blood sampling inclusion (Prealbumin analysis), Intervention at discharge : PUQE-form, Nutritional form and Blood sampling | Other: Hyperemesis gravidarum PUQE-form, nutritional form and Blood sampling |
| Control: Healthy pregnant women Outpatients NOT subjected to severe nausea and emesis (PUQE-score <13). PUQE-form inclusion (PUQE-score), Nutritional form inclusion, Blood sampling inclusion (Prealbumin analysis). |
Kritè kalifikasyon yo
| Laj ki kalifye pou etid | 18 Years Pou 18 Years |
| Sèks ki kalifye pou etid | Female |
| Metòd echantiyonaj | Non-Probability Sample |
| Aksepte Volontè Healthy | Wi |
| Kritè | Inclusion Criteria: - Pregnant women < 16 weeks of gestation - Admitted to hospital for hyperemesis gravidarum (HG group) with nausea and vomiting in pregnancy with at least two of following criteria; weight loss, dehydration, fluid-/electrolyte disturbances, ketonuria Exclusion Criteria: - Non-viable pregnancy diagnosed at time of inclusion - Unable to understand Norwegian - PUQE-score >= 13 (control group) - Nausea an vomiting in pregnancy caused by other conditions than Hyperemesis gravidarum |
Rezilta
Mezi Rezilta Prensipal yo
1. Prealbumin in normal pregnancy [Within 24h at inclusion]
Mezi Rezilta Segondè
1. Prealbumin related to nutritional parameters [Within 24h at inclusion]
2. Change in Prealbumin [Patients will be followed until discharge from hospital, a mean of 5 days, and blood sampling repeated at discharge]
3. Prealbumin in Hyperemesis gravidarum [Within 2h from admission to hospital]
