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Leukoaraiosis is a particular abnormal change in appearance of white matter near the lateral ventricles. It is often seen in aged individuals, but sometimes in young adults. On MRI, leukoaraiosis changes appear as white matter hyperintensities (WMHs). On CT scans, leukoaraiosis appears as hypodense periventricular white-matter lesions.The term 'leukoaraiosis' was coined in 1986 by Hachinski, Potter, and Merskey as a descriptive term for rarefaction ('araiosis') of the white matter, showing up as ...

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