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Phytochemistry 2005-Mar

Clerodane diterpenoids from Pulicaria wightiana.

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Biswanath Das
M Ravinder Reddy
R Ramu
N Ravindranath
H Harish
K V S Ramakrishna
Y Koteswar Rao
K Harakishore
U S N Murthy

Mo kle

Abstrè

Five clerodane diterpenoids have been isolated from the aerial parts of Pulicaria wightiana along with 3'5,6-trihydroxy-3,4',7-trimethoxyflavone and 2-methyl-5-hydroxy-chroman-4-one. The structures and stereochemistry of the compounds were established from spectral (mainly 1D and 2D NMR) studies. The last two compounds were not reported earlier from this plant. The antibacterial activity of the diterpenoids were studied.

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