Zhongguo zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban 1999-Feb

[Clinical and experimental study on treatment of asthma with juanxiao tablet].

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G Hong

Y Zhang

J Huang

ATIK: 11783305

BioSeek: 11783305

Mo kle

hypoxia

las

vitex negundo

vitex

antifonjik

Abstrè

OBJECTIVE

To evaluate the therapeutic effect of Juanxiao Tablet (JXT) in treating asthma.

METHODS

Clinical observation on 447 cases of asthma was done by double- or single-blind control method, and the therapeutic effect and safety of JXT were analysed. The effect of JXT in antiasthma, expectorant, antisepsis, hypoxia tolerance was studied, and its acute and chronic toxicity also examined.

RESULTS

The clinical control rate in patients treated with JXT was 38.2%, its markedly effective rate 31.2% and total effective rate 93.4%, while in patients treated with Oleum Vitex Negundo, the respective data were 13.3%, 20.0% and 68.5%. Results of pulmonary function and IgE measurement were consistent with clinical effect. Experimental study showed that the JXT has the action of anti-asthma, expectorant, antisepsis and hypoxia tolerance enhancement, its LD50 was (40.48 +/- 5.17) g/kg.

CONCLUSIONS

JXT is a new Chinese herbal preparation of good effect, less toxic-side reaction for asthma treatment.