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Onkologie 2012

Epithelioid hemangioendothelioma of the kidney treated with sunitinib.

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Yuri Tolkach
Sergey Petrov
Evelyne Lerut
Hendrik Van Poppel

Mo kle

Abstrè

BACKGROUND

Metastatic epithelioid hemangioendothelioma of the kidney is a rare malignant vascular tumor with a wide spectrum of behaviors.

METHODS

We present the case of a 53-year-old male patient with tumor metastases which developed after radical nephrectomy. We describe the immunohistochemistry profile of the tumor and the successful long-term results of treatment with sunitinib, a multi-targeted tyrosine kinase inhibitor. Also, we discuss the rationale for using this type of medication based on immunohistochemistry results.

CONCLUSIONS

To the best of our knowledge, this is the first reported case of metastatic renal epithelioid hemangioendothelioma treated successfully with sunitinib.

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