Agents and actions 1978-Oct
Protease inhibitors reduce the reverse passive Arthus reaction.
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Abstrè
Trasylol, ovomucoid, tranexamic acid and soybean inhibitor decrease the vascular permeability as measured by extravasation of 131I-albumin when injected with the antibody at induction of a reverse passive Arthus reaction in the rat skin. Trasylol given systemically also had a suppressive effect, similar to phenylbutazone. When the reaction was induced in the pleural cavity, both Trasylol and tranexamic acid reduced the influx of leucocytes.
