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Medicine 2017-Jan

Sarcomatoid carcinoma of the common bile duct: A case report.

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Shuisheng Zhang
Jia Jia
Xiaoning Bi
Qinglong Jiang
Yajie Zhao
Yingtai Chen
Quan Xu
Zhongmin Lan
Jianwei Zhang
Zhihui Zhang

Mo kle

Abstrè

BACKGROUND

Sarcomatoid carcinoma is an extremely rare lesion in the common bile duct (CBD).

UNASSIGNED

We present a case of sarcomatoid carcinoma of the distal CBD in a 51-year-old woman who presented with jaundice and abdominal pain. Whipple's operation was performed successfully. Microscopically, the tumor was a poorly differentiated carcinoma containing a component of sarcoma-like differentiation. The tumor cells displayed spindle-shaped nuclei with occasional mitotic figures. Cytokeratin (CK) 7, CK19, CK18, and pan-CK (AE1/AE3) staining was positive on immunohistochemistry. Vimentin and carcinoembryonic antigen (CEA) staining were also positive.

UNASSIGNED

Sarcomatoid carcinoma of the distal CBD.

METHODS

The patient received three cycles of chemotherapy after surgery.

RESULTS

The patient has experienced no adverse events in the 3 years post-surgery.

CONCLUSIONS

We present here a case report of sarcomatoid carcinoma of the distal CBD. The patient received chemotherapy after surgery, and was event-free for 3 years post-surgery, suggesting a relatively better prognosis, despite the infiltrative pattern of the tumor.

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