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Zhongguo Zhongyao Zazhi 2007-Jul

[Study on chemical constituents in rhigome of Ervatamia hainanensis].

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Shuang Liang
Hai-sheng Chen
Yong-sheng Jin
Li Jin
Jia Lu
Jing-ling Du

Mo kle

Abstrè

OBJECTIVE

To investigate the chemical constituents of the rhizome of Ervatamia hainanensis.

METHODS

The solvent extraction and silica column chromatography were used to separate the chemical constituents, and their structures were identified by physico chemical properties and spectra analysis.

RESULTS

Twelve compounds were isolated and their structures were identified as voacangine (1), ibogaine (2), ibogamine (3), coronaridine (4), 19-heyneanine (5), 19-epi-heyneanine (6), 3-hydroxyl coronaridine (7), coronaridine hydroxyindolenine (8), 3-(2-oxopropyl) coronaridine (9), vobasine (10), alpha-amyrin (11), alpha-amyrin acetate (12).

CONCLUSIONS

Compounds 1, 2, 6, 11 and 12 were first found from this plant.

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