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Natural Product Research 2014

Three new bioactive phenolic glycosides from Liparis odorata.

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Bin Li
Hongdong Liu
Dongming Zhang
Xuewen Lai
Bo Liu
Xianghong Xu
Peng Xu

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Abstrè

Chemical investigation of the ethanol extract from the whole plant Liparis odorata (Willd.) Lindl (orchid family) has led to the isolation of three new phenolic glycosides named liparisglycoside A-C (1-3) along with six known compounds (4-9). The structures of compounds were elucidated by means of extensive spectroscopic data analysis and comparison with the literature data. In addition, compounds 3 and 9 revealed inhibitory effects on lipopolysaccharide-stimulated nitric oxide production, and compounds 1, 3 and 9 displayed hypolipidaemic effects in in vitro bioassays.

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