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Journal of Asian Natural Products Research 2015

Three new iridoids from leaves of Cornus officinalis.

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Yong-Chao Li
Jing Yang
Xing-Gang Wu
Xin-Juan Xu
Qing-Yun Fu

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Abstrè

Three new iridoids, cornifins A-C (1-3), together with a known iridoid, were obtained from EtOAc layer of leaves of Cornus officinalis. The structures of new compounds were elucidated on the basis of extensive spectroscopic analyses. Compound 2 showed weak inhibitory activity against lung cancer cell line A-549 with IC50 value of 29.1 μM.

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