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adenylate kinase/seizures

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Dynamic expression of adenylate kinase 2 in the hippocampus of pilocarpine model rats.

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Studies have shown that adenylate kinase 2 (AK2) is released from the mitochondrial inner membrane space during neuronal apoptosis, which plays an important role in temporal lobe epilepsy (TLE). We investigated the expression of AK2 in the hippocampus of a pilocarpine model rats. Using reverse

Characteristics in limbic encephalitis with anti-adenylate kinase 5 autoantibodies.

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To report 10 patients with limbic encephalitis (LE) and adenylate kinase 5 autoantibodies (AK5-Abs). We conducted a retrospective study in a cohort of 50 patients with LE with uncharacterized autoantibodies and identified a specific target using immunohistochemistry, Western blotting,

Synaptosomal ATPase activities in temporal cortex and hippocampal formation of humans with focal epilepsy.

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Intact nerve endings (synaptosomes) have been isolated from spiking and non-spiking temporal cortex and hippocampus samples from 14 patients immediately after temporal lobectomy for intractable epilepsy. Synaptosomes were also prepared from frozen brain samples of humans with no known neurological
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