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ajmalicine/leukemia
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Alkaloids induce programmed cell death in bloodstream forms of trypanosomes (Trypanosoma b. brucei).
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The potential induction of a programmed cell death (PCD) in Trypanosoma b. brucei by 55 alkaloids of the quinoline, quinolizidine, isoquinoline, indole, terpene, tropane, steroid, and piperidine type was studied by measuring DNA fragmentation and changes in mitochondrial membrane potential. For
Synergistic and cytotoxic action of indole alkaloids produced from elicited cell cultures of Catharanthus roseus.
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BACKGROUND
Catharanthus roseus (L.) G. Don (Apocynaceae) is a medicinal plant that produces more than 130 alkaloids, with special attention given to the production of the anti-hypertensive monomeric indole alkaloids, serpentine and ajmalicine, and the antitumor dimeric alkaloids, vinblastine and
The effects of UV-B stress on the production of terpenoid indole alkaloids in Catharanthus roseus hairy roots.
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In nature, plants generate protective secondary metabolites in response to environmental stresses. Such metabolites include terpenoid indole alkaloids (TIAs), which absorb UV-B light and serve putatively to protect the plant from harmful radiation. Catharanthus roseus plants, multiple shoot
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* Tout enfòmasyon baze sou rechèch syantifik pibliye
