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Shifts in the normal balance of neurovegetative and hormonal regulations, modifications in the ionic composition of the plasma and pathological changes such as ischaemia, hypoxia and hypercapnia may lead to changes in permeability of the cardiac cell membranes to different ions, resulting in
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Neuropathy is a common complication of Type 1 and Type 2 diabetes. In the peripheral nerve, persistent hyperglycaemia leads to metabolic and vascular disorders responsible for nerve fibre abnormalities. Genetic predisposition has been mentioned more recently. Among metabolic factors, an increase of
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