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alpha onocerin/ononis
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Comprehensive spectroscopic investigation of alpha-onocerin.
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A detailed NMR and MS analysis of alpha-onocerin was performed in order to provide precise phytochemical reference for structure identification and quality control of this analytical lead compound from Ononis spinosa the roots of which are widely used as a diuretic drug. Unambiguous 1H- and 13C-NMR
A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin.
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8,14-seco-Triterpenoids are characterized by their unusual open C-ring. Their distribution in nature is rare and scattered in taxonomically unrelated plants. The 8,14-seco-triterpenoid α-onocerin is only known from the evolutionarily distant clubmoss genus Lycopodium and the leguminous genus Ononis,
The enzymic conversion of squalene, 2(3),22(23)-diepoxide to alpha-onocerin by a cell-free extract of Ononis spinosa.
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New insights into the acetylcholinesterase inhibitory activity of Lycopodium clavatum.
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Looking for acetylcholinesterase (AChE) inhibiting compounds within the plant kingdom, we came across the triterpene alpha-onocerin, which has recently been described as the active principle (IC(50) of 5.2 microM) of Lycopodium clavatum L. In order to discover related terpenoid structures with
[Chemical composition and microstructural peculiarities of overground and underground vegetative organs of field restharrow (Ononis arvensis L.)].
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The paper presents the results of the study of anatomy and chemical composition of Field Restharrow (Ononis arvensis L.). The existence of triterpene alcohol α-onocerin and isoflavons in the overground organs of the plant is established by chemical analysis. Oxycumarines - scopoletin and scopolin
Root Extracts From Ononis spinosa Inhibit IL-8 Release via Interactions With Toll-Like Receptor 4 and Lipopolysaccharide
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Extracts from the roots of Ononis spinosa L. (restharrow roots) are traditionally used for the treatment of patients with urinary tract infections due to its mild diuretic activity, caused by the inhibition of renal human hyaluronidase-1 by isoflavonoids. Preliminary studies also indicated
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