aristolactam/aristolochia

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Fate of Ingested Aristolactams from Aristolochia chilensis in Battus polydamas archidamas (Lepidoptera: Papilionidae).

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We performed a sequestration study of aristolactams (ALs) from Aristolochia chilensis in Battus polydamas archidamas (Lepidoptera: Papilionidae) by examining the AL content of the plant, fifth instar larvae, osmeterial secretion, pupae, exuviae and feces. Aristolactam-I (AL-I) and aristolactam-II

Aristolactams and Alkamides of Aristolochia gigantea.

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A new aristolactam, aristolactam 9-O-β-D-glucopyranosyl-(1→2)-β-D-glucoside, and two alkamides, N-cis- and N-trans-p-coumaroyl-3-O-methyldopamine, were isolated from stems of Aristolochia gigantea, together with the known compounds allantoin, E-nerolidol, β-sitosterol, (+)-kobusin, (+)-eudesmin,

A new aristolactam-type alkaloid from the roots of Aristolochia fangchi.

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Phytochemical investigation of 85% ethanol extracts from the roots of Aristolochia fangchi yielded a new aristolactam derivative named 6-methoxyl aristolactam I N-β-glucoside (1), together with four known compounds, aristolactam IVa (2), aristolactam I-β-D-glucoside (3), aristolactam I (4), and

Isolation, structural elucidation and anti-inflammatory activity of astragalin, (-)hinokinin, aristolactam I and aristolochic acids (I & II) from Aristolochia indica.

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Astragalin was isolated for the first time along with (-)hinokinin, aristolactam I and aristolochic acids (I & II) from the extracts of Aristolochia indica L. using a new, efficient preparative HPLC method. A reversed-phase HPLC method of analysis was developed to analyse the isolated compounds. The

Aristolochic acids, aristolactam alkaloids and amides from Aristolochia kankauensis.

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Fourteen aristolochic acid derivatives: ariskanins A-E, 3-hydroxy-4-methoxy-10-nitrophenanthrene-1-carboxylic acid methyl ester, aristolochic acid-II methyl ester, aristolochic acid-IV methyl ester, aristolochic acid-C, -I, -II, -III, -IV, -IVa; nine aristolactam alkaloids: aristolactam,

Aristolochic acids and aristolactams from the seeds of Aristolochia baetica.

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Identifying Cysteine, N-Acetylcysteine, and Glutathione-Conjugates as Novel Metabolites of Aristolochic Acid I: Emergence of a New Detoxification Pathway.

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There is accumulating evidence that Balkan endemic nephropathy (BEN) is an environmental disease caused by aristolochic acids (AAs) released from the decomposition of Aristolochia clematitis L., an AA-containing weed that grows abundantly in the Balkan Peninsula. AA exposure has also been associated

[Studies on the chemical constituents from the fruit of Aristolochia debilis].

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OBJECTIVE To study the chemical constituents of the fruit of Aristolochia debilis. METHODS The compounds were isolated by chromatographic techniqcue and crystal methods, the structures were elucidated by spectrum analysis. RESULTS 8 compounds were isolated from the dry fruit of Aristolochia debilis

A new biflavonoid from Aristolochia contorta.

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From the fruits of Aristolochia contorta Bge, beside the known aristolochic acids IVa and VII, aristolactam-N-beta-D-glucopyanoside, aristoloctam Ia N-beta-D-glucopyanoside, pinitol and daucosterol, a new biflavonoid was isolated. Its structure was determined as

Sulfur-Containing Aristoloxazines and Other Constituents of the Roots of Aristolochia orbicularis.

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Six new compounds, aristoloxazine A (1), aristoloxazine B (2), 7-methoxytaliscanine (3), humul-7-en-1,4,11-triol (4), 8-hydroxy-β-logipinene (5), and 1β-hydroxy-4(14)-eudesmene (6), corresponding to two sulfur-containing aristoloxazines (1 and 2), an aristolactam (3), and three sesquiterpenes (4-6)

A new acylated N-glycosyl lactam from Aristolochia contorta.

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A new acylated glycoside isolated from the roots of Aristolochia contorta (Aristolochiaceae), has been characterized as aristolactam N-(6'-trans-p-coumaroyl)-beta-D-glucopyranoside [2]. Aristolactam-N-beta-D-glucopyanoside [1] was also isolated from the same source. Compound 2 showed relatively

The alkaloids and other constituents from the root and stem of Aristolochia elegans.

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Two new aristolactams, aristolactam E (1) and aristolactam-AIIIa-6-O-beta-D-glucoside (2), three novel benzoyl benzyltetrahydroisoquinoline ether N-oxide alkaloids, aristoquinoline A (3), aristoquinoline B (4), and aristoquinoline C (5), and a new biphenyl ether, aristogin F (6), together with 62

[Chemical constituent from fruit of Aristolochia contorta].

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OBJECTIVE To study the chemical constituents of the fruit of Aristolochia contorta. METHODS The compounds were isolated by chromatographic techniques and crystalization, the structures were elucidated by spectrum analysis. RESULTS Fifteen compounds were isolated from the dry fruit of A. contorta,

Role of environmental toxins in endemic (Balkan) nephropathy. October 2006, Zagreb, Croatia.

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An international symposium, held in Zagreb, Croatia, in October 2006, brought together basic scientists and clinical investigators engaged in research on endemic (Balkan) nephropathy, a chronic renal tubulointerstitial disease of previously unknown cause that often is accompanied by upper urinary

Characterization and quantitation of aristolochic acid analogs in different parts of Aristolochiae Fructus, using UHPLC-Q/TOF-MS and UHPLC-QqQ-MS.

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Aristolochiae Fructus, a Chinese herbal medicine derived from the fruit of Aristolochia contorta Bge., contains nephrotoxic aristolochic acid analogues (AAAs). According to ancient medical texts, various medicinal parts of the fruit of A. contorta were ever used. In order to reveal which part could

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