biliary atresia/obesity

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Overweight, central obesity, and cardiometabolic risk factors in pediatric liver transplantation.

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PTMS describes the presence of ≥3 cardiometabolic risk factors that include obesity, hypertension, dyslipidemia, and IR. The prevalence of the clustering of ≥3 cardiometabolic risk factors or central obesity has not been studied in pediatric LT recipients. Single-center, cross-sectional

Obesity after pediatric liver transplantation: prevalence and risk factors.

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OBJECTIVE Pediatric obesity has become a significant public health concern. The historical focus in pediatric liver transplant (LT) has been undernutrition, with limited knowledge regarding obesity. Therefore, we sought to determine the prevalence of obesity in pediatric LT, compare it to National

Body Composition of Infants With Biliary Atresia: Anthropometric Measurements and Computed Tomography-Based Body Metrics

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Objectives: Biliary atresia (BA) causes neonatal cholestasis that requires hepatoportoenterostomy or liver transplantation (LT) for long-term survival. Nutritional optimisation is necessary as sarcopenia and sarcopenic obesity have been

Gallbladder disease in childhood.

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Seventy-seven children less than 19 years old underwent cholecystectomy during a 12-year period at UCLA Medical Center. Forty-four had calculous cholecystitis; five had acalculous cholecystitis; and 28 underwent cholecystectomy with other major biliary surgery. In more than half of the patients with

Single Nucleotide Polymorphism (SNP) in the Adiponectin Gene and Cardiovascular Disease.

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Dear Editor, The recent article by Mohammadzadeh et al.[1] on the latest issue of this Journal showed that the T allele +276G/T SNP of ADIPOQ gene is more associated with the increasing risk of coronary artery disease (CAD) in subjects with type 2 diabetes. Adipocytes were described in myocardial

A Bibliometric Analysis of Clinical and Translational Research in Pediatric Gastroenterology From 1970 to 2017.

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OBJECTIVE Pediatric gastroenterology is a clinical and research discipline principally developed over the past 50 years. Bibliometric methods provide quantitative analysis and identify research trends. Study aims were to characterize the growth and trends in pediatric gastroenterology clinical and

Wound healing in the biliary tree of liver allografts.

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An increasing need for liver transplantation requires evaluation and triage of organs harvested from "extended criteria" donors. Although there is currently no widely accepted definition, most would agree that "extended criteria" includes organs donated by individuals that are old (>65 years),

De novo fatty liver due to vascular complications after liver transplantation.

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BACKGROUND The incidence, risk factors, and natural history of de novo nonalcoholic fatty liver disease (NAFLD) after liver transplantation have not been well described. In this report we examined the risk factors and demographic characteristics of 3 patients. METHODS During a 16-year period, we

Weaning of immunosuppression in long-term liver transplant recipients.

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Seventy-two long-surviving liver transplant recipients were evaluated prospectively, including a baseline allograft biopsy for weaning off of immunosuppression. Thirteen were removed from candidacy because of chronic rejection (n = 4), hepatitis (n = 2), patient anxiety (n = 5), or lack of

Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1.

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Prohibitin-1 (PHB1) is an evolutionarily conserved pleiotropic protein that participates in diverse processes depending on its subcellular localization and interactome. Recent data have indicated a diverse role for PHB1 in the pathogenesis of obesity, cancer, and inflammatory bowel disease, among

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