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biliary atresia/proline

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Bile duct enlargement by infusion of L-proline: potential significance in biliary atresia.

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The normal signals of control of bile duct morphogenesis and growth are unknown. Consequently, aberrant development is poorly understood, as for example in those infants with biliary atresia or hypoplasia. A previous report by Isseroff et al., showed that a possible mechanism for the common bile

The influence of various amino acids on the extrahepatic bile ducts in newborn mice--an experimental study.

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Excess proline in adult animals is associated with extrahepatic biliary hyperplasia. Possible therapeutic application of this amino acid in biliary atresia was postulated. In order to test whether excess proline had an influence on the development of the extrahepatic bile ducts, pregnant mice were
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