biotinidase deficiency/protease

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Examination of the signal peptide region of human biotinidase using a baculovirus expression system.

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Biotinidase deficiency is an autosomal recessive disorder of biotin recycling. Biotinidase cleaves the biotin from biocytin or short biotinyl-peptides to replenish the free biotin pool, or it can transfer the vitamin to specific proteins. The cDNA for human serum biotinidase has two in-frame start

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Herbal & Natural Medicine

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