cataract/albumin

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Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac.

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Diclofenac instillation has been used widely in cataract surgery to prevent postoperative inflammation. Since diclofenac binds strongly to albumin in the circulation, it does not have a sufficient effect on patients in whom diclofenac binds strongly to albumin in the aqueous humor. A decrease in

Lactoferrin and serum albumin in the conjunctival fluid of eyes operated for senile cataract.

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The concentrations of serum albumin (SA) in the conjunctival fluid were measured in 25 patients before surgery and in the post-operative period following cataract extraction. We found a significant increase in mean tear fluid SA concentration on the first post-operative day. The SA concentration

Effect of high-glucose levels on protein oxidation in cultured lens cells, and in crystalline and albumin solution and its inhibition by vitamin B6 and N-acetylcysteine: its possible relevance to cataract formation in diabetes.

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Diabetic patients have elevated levels of glucose in their blood and other body fluids. This project studied the effect of high-glucose concentrations (HG) on the protein oxidation in cultured lens cells and in crystalline protein solution. In addition, we also examined the effect of HG on the

Effect of diabetic retinopathy on redox state of aqueous humor and serum albumin in patients with senile cataract.

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OBJECTIVE To investigate the oxidative status of albumin in the aqueous humor and serum of senile cataract patients with diabetes in order to clarify the pathogenesis of this condition. METHODS High-performance liquid chromatography (HPLC) was employed to measure the reduced form of albumin

Age-related cataract and serum albumin concentration.

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OBJECTIVE Searching for new factors which might be important in age-related cataractogenesis. A possible association between serum albumin concentration and age-related cataract has already been recognized, but their relationship is not quite apparent. METHODS Retrospective cross-section study on

Difference in redox status of serum and aqueous humor in senile cataract patients as monitored via the albumin thiol-redox state.

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OBJECTIVE To clarify the redox states of the aqueous humor and serum in senile cataract patients. METHODS We analyzed the reduced and oxidized albumin fractions in 58 patients. The patients had no detectable evidence of other eye or systemic diseases and were divided into two age groups (53-75 and

Albumin and transthyretin as risk factors for cataract: the POLA study.

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OBJECTIVE To assess the associations of markers of protein nutrition (plasma albumin and transthyretin) with cataract. METHODS The Pathologies Oculaires Liées à l'Age (POLA) Study (1995-1997) is a population-based study on age-related eye diseases, performed in 2584 residents of Sète (South of

Association between cataract progression and ischemia-modified albumin in relation to oxidant-antioxidant profiles in the serum, aqueous humor, and lens.

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OBJECTIVE To evaluate the levels of ischemia-modified albumin (IMA) in relation to oxidant-antioxidant profiles in the serum, aqueous, and lens in cataract patients. METHODS Department of Ophthalmology, Menoufia University, Shebin El Kom, Menoufia, Egypt. METHODS Prospective case

A study of factors related to the incidence of cataract in patients with non-insulin dependent diabetes mellitus.

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OBJECTIVE To investigate the factors related to the development of cataract in patients with non-insulin dependent diabetes mellitus(NIDDM). METHODS 792 NIDDM patients received ophthalmologic examinations including visual acuity, external status of the eyes, slit lamp microscopy and ophthalmoscopy.

Biochemical factors in the lens opacities. Case-control study. The Lens Opacities Case-Control Study Group.

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OBJECTIVE To evaluate associations with biochemical indicators of nutritional and other risk factors in the Lens Opacities Case-Control Study. METHODS Case-control study. METHODS The Lens Opacities Case-Control Study determined risk factors for cortical, nuclear, and posterior subcapsular opacities

Spectroscopic Studies on the Molecular Ageing of Serum Albumin.

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Pathological states in the organism, e.g., renal or hepatic diseases, cataract, dysfunction of coronary artery, diabetes mellitus, and also intensive workout, induce the structural modification of proteins called molecular ageing or N-A isomerization. The aim of this study was to analyze the

Immune deficiency of cataract Shionogi (CTS) mouse. II. Impaired in vivo T cell-mediated immune response.

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Our previous study demonstrated that cataract Shionogi (CTS) mice, an inbred strain related to non-obese diabetic (NOD) mice, are T lymphocytopenic and that their T cell-mediated in vitro reactions, such as proliferative responses of spleen cells to T cell mitogens and alloantigens or production of

Some plasma constituents correlate with human cataract location and nuclear colour.

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OBJECTIVE To look for differences in levels of various plasma constituents between pair-matched controls and patients who had cataracts classified by location and appearance of lens opacity and nuclear colour in order to identify systemic risk factors. METHODS One thousand patients were taken from

Aqueous and serum β(2)-microglobulin levels in patients with senile cataracts, and cataracts associated with uveitis or atopy.

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β(2)-Microglobulin (β(2) M) has been reported to be elevated in patients with a variety of neoplasms and inflammatory disorders, and is believed to be a sensitive although nonspecific marker for lymphocyte activation and/or proliferation. In order to investigate the role of inflammation in the

Ocular-surface temperature modification by cataract surgery.

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To analyze ocular-surface temperature changes after microincision cataract surgery and to correlate them with surgical, clinical, and laboratory parameters. Ophthalmology Unit, Saint Orsola-Malpighi Hospital, Bologna, Italy. Prospective case series. Patients affected by monolateral senile cataract

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