chordoma/carbohydrate

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Detection and distribution of the carbohydrate binding protein galectin-3 in human notochord, intervertebral disc and chordoma.

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Galectin-3 is an endogenous carbohydrate-binding protein which plays a role in cell differentiation, morphogenesis and cancer biology. We investigated the occurrence and distribution of galectin-3 in the embryonic and fetal human notochord, the developing human vertebral column, adult intervertebral

Galectin-3: a biologic marker and diagnostic aid for chordoma.

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Galectin-3 is a beta-galactoside binding protein. Its expression is quantitatively and qualitatively altered during self-proliferation, malignant transformation, and tumor progression. Galectin-3 is a lectin-related molecule. Lectins are proteins that bind specific carbohydrate structures. Although

Differential proteomic profiling of primary and recurrent chordomas.

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Chordomas are locally destructive tumors with high rates of recurrence and a poor prognosis. The mechanisms involved in chordoma recurrence remain largely unknown. In the present study, we examined the proteomic profile of a chordoma primary tumor (CSO) and a recurrent tumor (CSR) through mass

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Herbal & Natural Medicine

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