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cnestis ferruginea/anticonvulsant

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[Anticonvulsant activity of Cnestis ferruginea DC., Connaraceae].

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ETHNOPHARMACOLOGY RELEVANCE: the root decoction of Cnestis ferruginea Vahl ex DC (Connaraceae) is widely used in traditional African medicine for the treatment of various ailments including pain, inflammation and epilepsy. We have earlier reported anticonvulsant effect of Cnestis

[Demonstration and partial purification of a convulsant from Cnestis glabra (Connaracea): effect on cells in culture].

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A dialysable and thermostable compound was partially purified from Cnestis glabra (Connaracea) seeds. It is insoluble in organic solvents. At a dose corresponding to 0.5 g of seeds it has a lethal effect on mice after convulsive attacks. Sodium dipropylacetate, an anticonvulsive agent prevents the
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