cryptosporidiosis/albumin

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Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

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Cryptosporidium parvum is an important human pathogen and potential bioterrorism agent. This protozoan parasite cannot salvage guanine or guanosine and therefore relies on inosine 5'-monophosphate dehydrogenase (IMPDH) for biosynthesis of guanine nucleotides and hence for survival. Because C. parvum

Prevalence of enteric pathogens in HIV-related diarrhea in the midwest.

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HIV disease is often associated with the condition of diarrhea, which may be accompanied by enteric infection or gastrointestinal tumor. This study prospectively investigated 27 episodes of chronic diarrhea in 24 patients with HIV infection. Upper endoscopy and sigmoidoscopy with biopsies at three

Macronutrient intake and malabsorption in HIV infection: a comparison with other malabsorptive states.

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BACKGROUND Wasting is a major complication of HIV infection. The role of malabsorption in wasting is controversial. OBJECTIVE To assess oral intake and malabsorption in a cohort of weight losing HIV infected patients, with or without chronic diarrhoea. METHODS A prospective study using a predefined

Mannose-binding lectin is a component of innate mucosal defense against Cryptosporidium parvum in AIDS.

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OBJECTIVE Nonimmune mechanisms of mucosal defense seem to be biologically important and might explain the observed variability in the course of enteric infection in immunodeficiency. Mannose-binding lectin (MBL) deficiency is associated with persistent diarrhea in children. We found that genetic

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