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Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis.
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Sterol 14alpha-demethylase encoded by CYP51 is a mixed-function oxidase involved in sterol synthesis in eukaryotic organisms. Completion of the Mycobacterium tuberculosis genome project revealed that a protein having homology to mammalian 14alpha-demethylases might be present in this bacterium.
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