d xylose/atrophy

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Improved screening for intestinal villous atrophy by D-xylose breath test.

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The hydrogen breath test (H2BT) with D-xylose has proven valid in both early recognition and follow-up of intestinal malabsorption. To further evaluate the specificity of the H2BT with D-xylose in the diagnosis of intestinal malabsorption as compared to the conventional urinary D-xylose test, we

The 1-hour D-xylose test in the diagnosis of villous atrophy.

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The results obtained in 40 cases of intestinal mucosal biopsy and parallel 1-hour D-xylose test are presented. Of 40 patients, 15 had subtotal villous atrophy, while in 25 the villous structure was intact. Among the 15 patients with villous atrophy 10 gave D-xylose values of less than 20 mg per dl.

Plasma citrulline as a quantitative biomarker of HIV-associated villous atrophy in a tropical enteropathy population.

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OBJECTIVE Studies have shown that the circulating citrulline concentration is decreased in patients with proximal small bowel villous atrophy from coeliac disease and more so in patients with extensive damage to the intestinal mucosa, but there have been few data on HIV enteritis and tropical

Purification and cDNA cloning of UDP-D-glucuronate carboxy-lyase (UDP-D-xylose synthase) from pea seedlings.

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Uridine diphospho-D-glucuronate carboxy-lyase (UDP-D-xylose synthase; EC 4.1.1.35), which catalyzes the conversion of UDP-D-glucuronate to UDP-D-xylose, was purified to apparent homogenity from pea (Pisum sativum L.) seedlings. The pH optimum for enzyme activity was around 5-6, and the activity was

Age-dependent retinal capillary pericyte degeneration in galactose-fed dogs.

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The galactose-fed beagle develops diabetes-like microvascular changes that are histologically and clinically similar in appearance to all stages of human diabetic retinopathy. This animal model is extremely useful for evaluating drugs for the treatment of diabetic retinopathy; however, the time

[The value of the d-xylose loading test in the diagnosis of malabsorption syndromes].

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The test of d-xylose concentration in blood has been used for approximately two decades for the examination of the absorption. The authors compared in 261 cases the total d-xylose blood level with the histological picture of the small intestine. Good correlation was observed between the 2

Comparison of the D-xylose and polyethylene glycol absorption tests as indicators of mucosal damage in infants with chronic diarrhea.

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The determination of serum levels of D-xylose and the urinary excretion of an orally administered mixture of low-molecular-weight polyethylene glycol were compared to assess their sensitivity to predict small-bowel mucosal damage. Eighteen infants with severe diarrhea and villus atrophy were

Hydrogen breath test with D-xylose for celiac disease screening is as useful in the elderly as in other age groups.

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Up to one fifth of celiac disease patients are diagnosed after the age of 60. The hydrogen breath test with D-xylose as substrate (xylose-BT) has proved useful for the diagnosis of adult celiac disease. Our aim was to determine the potential influence of age-related intestinal mucosal changes on the

Failure of laboratory and radiological studies to predict jejunal mucosal atrophy.

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Of 58 children with suspected malabsorption, 27 were shown to have subtotal or partial atrophy, and 31 had normal mucosal histology. Oral glucose tolerance tests, faecal fat excretion, D-xylose excretion tests, Prosparol absorption studies, haematological investigations, and radiological examination

Villus atrophy and malabsorption in a rhesus monkey.

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Villus atrophy involving the proximal small intestine was diagnosed in a rhesus monkey (Macaca mulatta) at necropsy. A juvenile, male, captive-born monkey exhibited weight loss, hypoalbuminemia, patchy alopecia, eosinophilia, and vomiting. D-xylose absorption was impaired. Contrast radiography

The D-xylose test in coeliac disease.

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The results of more than 500 D-xylose loading tests are described. In almost half of the cases proven or suspected to be coeliac disease, the blood xylose level was low. In 69 patients the result was compared to that of small bowel biopsy. Abnormal levels were found in 98% of total or subtotal

Giardiasis causing chronic diarrhoea in suburban Copenhagen: incidence, physical growth, clinical symptoms and small intestinal abnormality.

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During a six-year period, 29 children (aged 0.7-13.5 years, mean 3.3 years) suffering from chronic diarrhoea due to giardiasis were studied. The incidence of this illness was 81 per 1,000,000 children aged 0- < 7 years per year. According to growth charts, relative height and weight of the patients

[Giardiasis in children with chronic diarrhea. Incidence, growth, clinical symptoms and changes in the small intestine].

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During a six-year period, 29 children (aged 0.7-13.5 years, mean 3.3 years) suffering from chronic diarrhoea due to giardiasis were studied. The incidence of this illness was 81 per 1,000,000 per year among children aged 0- < 7 years. According to growth charts, relative height and weight of the

Colonic lymphoma producing alpha-chain disease protein.

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Alpha-chain disease with involvement of small intestine-resulting in characteristic villus atrophy and malabsorption has not been reported in this country. We studied a 57-yr-old male who presented with a polypoid tumor of the hepatic flexure of the colon. There was no evidence of malabsorption as

Enteropathy associated with the acquired immunodeficiency syndrome.

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To explore the effect of the acquired immunodeficiency syndrome on gastrointestinal structure and absorption, the cases of 12 homosexual men with the syndrome and 11 homosexual controls were studied. Seven patients had diarrhea with weight loss. Bacterial or parasitic infections were not detected.

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