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Remission induction therapy of untreated acute myeloid leukemia using a non-cytarabine-containing regimen of idarubicin, etoposide, and carboplatin.

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BACKGROUND The safety and efficacy of idarubicin, etoposide, and carboplatin as remission induction therapy for patients younger than 60 years with untreated acute myeloid leukemia was studied as an alternative to standard regimens based on cytarabine plus anthracycline. METHODS Eligible patients

Acute radiation enteritis caused by dose-dependent radiation exposure in dogs: experimental research.

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Accidental or intended radiation exposure in mass casualty settings presents a serious and on-going threat. The development of mitigating and treating agents requires appropriate animal models. Unfortunately, the majority of research on radiation enteritis in animals has lacked specific assessments

Whipple's disease. Description of a case and survey of the literature.

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A case of Whipple's disease (WD) personally observed is described. A 28-year-old male was admitted to hospital for evaluation of weakness, intermittent fever and weight loss arisen since a month. On clinical investigation, he complained of vomit and diarrhea since three months. He had neither

[Malabsorption in systemic lupus erythematosus].

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A 25-year-old man, who was admitted for evaluation of arthralgia and fever of 2-weeks duration, complained of a 10 kg weight loss during the previous weeks. Systemic lupus erythematosus (SLE) was diagnosed on the basis of leukopenia, LE cells, antinuclear antibodies, antibodies to double-stranded

[Experimental study on gut tolerance to early enteral nutrition following intestinal ischemia/reperfusion].

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OBJECTIVE To investigate the effects of early enteral nutrition (EEN) on intestinal function and gut tolerance after intestinal ischemia/reperfusion (I/R) injury. METHODS Twenty-four male dogs were randomly divided into three groups: EEN only, I/R only and I/R+EEN. The superior mesenteric artery

Villus atrophy and malabsorption in a rhesus monkey.

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Villus atrophy involving the proximal small intestine was diagnosed in a rhesus monkey (Macaca mulatta) at necropsy. A juvenile, male, captive-born monkey exhibited weight loss, hypoalbuminemia, patchy alopecia, eosinophilia, and vomiting. D-xylose absorption was impaired. Contrast radiography

Food-induced malabsorption syndromes.

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A syndrome of chronic diarrhea, vomiting, and failure to thrive was described 35 years ago. The syndrome was caused by damage in the jejunum after ingestion of cow's milk. Symptoms appeared in young infants shortly after introduction of cow's milk formula. Patients had moderate steatorrhea,

Gastrointestinal Manifestations in Satoyoshi Syndrome: A Systematic Review

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Background: Satoyoshi syndrome (SS) [OMIM 600705; ORFHA 3130] is a multisystemic disease with a probable autoimmune basis, whose main symptoms are muscle spasms, alopecia, diarrhea and skeletal alterations. Chronic diarrhea may be severe and result in malnutrition,

Clinical, endoscopic, and histological differentiation between celiac disease and tropical sprue: A systematic review.

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OBJECTIVE While the prevalence of celiac disease (CD) is increasing globally, the prevalence of tropical sprue (TS) is declining. Still, there are certain regions in the world where both patients with CD and TS exist and differentiation between them is a challenging task. We conducted a systematic

Intestinal mucosal dysfunction and infection during remission-induction therapy for acute myeloid leukaemia.

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Intestinal barrier function was prospectively examined in the course of a clinical trial evaluating the efficacy and safety of lisofylline for reducing cytotoxic therapy-induced intestinal epithelial damage-related infectious morbidity in patients receiving standard remission-induction therapy for

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