decenoic acid/lung neoplasms

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Induction of Human-Lung-Cancer-A549-Cell Apoptosis by 4-Hydroperoxy-2-decenoic Acid Ethyl Ester through Intracellular ROS Accumulation and the Induction of Proapoptotic CHOP Expression.

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Royal jelly, a natural product secreted by honeybees, contains several fatty acids, such as 10-hydroxy-2-decenoic acid (DE), and shows anti- and pro-apoptotic properties. 4-Hydroperoxy-2-decenoic acid ethyl ester (HPO-DAEE), a DE derivative, exhibits potent antioxidative activity; however, it

Inhibitory effects of 4-hydroperoxy-2-decenoic acid ethyl ester on phorbol ester- and TGF-β1-induced MMPs expression.

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Matrix metalloproteinases (MMPs), zinc-containing proteinases, play a critical role in tumor progression by degrading extracellular matrix components. MMP2 and MMP9 are secreted from tumor-associated macrophages as well as tumor cells and have been implicated in the formation of the tumor

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