A self-powered compression device for use in promoting circulation, said device embodying a plurality of inflatable sleeves arranged sequentially for applying compression to a body or limb and which further comprises a pump, a piping system and a bandage or boot to enclose the device in its entirety. A method for using self-generated pressure in promoting circulation in conditions including but not limited to, lymphatic and traumatic edemas, venous disorders, limb ulcers, varicose veins, muscle fatigue, sports medicine, cellulite treatment, diabetic feet, feet massage for recreation or cosmetic enhancements.

C-Boot Ltd

Self-powered compression devices and methods for promoting circulation and therapeutic compression

The present invention is directed to methods for systematic identification of cellular ligands, disease-associated ligands, age-related ligands and receptor-specific ligands. Disease-associated ligands are promising targets to develop novel ligand-based therapies. The methods are broadly applicable to any type of cells or diseases in in vitro and in vivo settings. This invention further used the methods to identify Scg3 as a disease-related angiogenic factor for the therapy of diabetic retinopathy, diabetic macular edema, proliferative diabetic retinopathy, vascular age-related macular degeneration, diabetic foot and cancers.

diabetic foot/edema

Self-powered compression devices and methods for promoting circulation and therapeutic compression

Quantitative ligandomics for systematic identification of therapeutic ligands

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