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dihydroagarofuran/inflammation

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Anti-inflammatory sesquiterpene pyridine alkaloids from Tripterygium wilfordii.

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During a screening procedure involving higher plants to find novel candidates for use as anti-inflammatory agents, Tripterygium wilfordii Hook. f. was shown to exhibit considerable inhibitory activity. Five new sesquiterpene pyridine alkaloids, tripterygiumines S-W (1-4,15), along with 14 known
Triptersinoids A-E (1-5), five undescribed highly oxygenated dihydro-β-agarofuran type sesquiterpenoid polyesters, along with three known analogues were isolated from the aqueous EtOH extracts of the dried leaves of Tripterygium wilfordii. Spectroscopic techniques were used for the elucidation of

Anti-inflammatory sesquiterpene derivatives from the leaves of Tripterygium wilfordii.

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Twelve new dihydroagarofuran sesquiterpene polyol esters, triptersinines A-L (1-12), and eight known sesquiterpene pyridine alkaloids were isolated from the leaves of Tripterygium wilfordii. Their structures were elucidated on the basis of spectroscopic analyses, including UV, IR, and NMR
As part of a bioprospecting program aimed at exploration of undiscovered or/and bioactive compounds from the plants located in Yunnan province (China), a phytochemical investigation of a 70% ethanol extract of the stems of Tripterygium hypoglaucum led to the isolation of two previously unreported

Cyclooxygenase inhibitory compounds from Gymnosporia heterophylla aerial parts.

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Gymnosporia heterophylla (Celastraceae) is an African medicinal plants used to treat painful and inflammatory diseases with partial scientific validation. Solvent extractions followed by repeated chromatographic purification of the G. heterophylla aerial parts led to the isolation of one new
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