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36 patients with essential hypertension and 15 of their adult descendants were investigated and compared with age-matched control groups of 33 and 15 healthy subjects, respectively. The ventilatory response to oxygen breathing and to progressive normo- und isocapnic hypoxia were studied. The
An increased sympathetic nervous response to hypoxia and reduced beta-adrenergic receptor function have been reported in hypertension. This study examines the relationship between hypoxia and beta-adrenergic receptor function in sixteen normotensive and eight hypertensive subjects. We measured the
We investigated the ventilatory responses to hypoxia and hypercapnia in patients with essential hypertension (HT) as compared with healthy subjects (NV). Further, to evaluate the contribution of the peripheral chemoreceptors to ventilatory response, we used a withdrawal test. Hypoxic ventilatory
The aim of the study was to determine the efficiency of enalapril therapy during 24-hours blood pressure monitoring. A group of healthy subjects (C, n = 11), a group of patients with essential hypertension without therapy (EH, n = 9) and a group of patients with essential hypertension II (WHO)
Clinical and functional condition was examined for 75 patients with essential hypertension stage I and II who had developed adaptation to normobaric cyclic-fractionated hypoxia. The latter was produced by gas hypoxic mixture (10% oxygen, 90% nitrogen) in its inhalation. A pronounced positive effect
A randomized parallel study was performed to compare the antihypertensive effect of normobaric hypoxia and low energetic laser irradiation in 57 patients with essential hypertension stage I using 24-hour blood pressure monitoring. High hypotensive efficacy of both methods is demonstrated. A course
The aim of this study was to investigate whether there are differences between particular characteristics of the ventilatory responses to acute hypoxia and hyperoxia in primary hypertensive and normotensive states which might indicate significant differences in arterial chemoreceptor reflex
The authors studied the efficiency of preventive usage of intermittent normobaric hypoxic hypoxia (INHH) in 44 pregnant females at high risk for late gestosis in presence of essential hypertension, stages I-II, and hypertensive type of neurocirculatory asthenia. The authors paid attention to a
In 135 patients of advanced and senile age with essential hypertension hemodynamics and gas composition of the blood were investigated by the methods of the dye dilution after Stewart-Hamilton, Sechenov-van Slyke and micro-Astrup. The patients of this age category were found to suffer predominantly
Patients with essential hypertension were exposed to periodic hypoxia in a pressure chamber. It is shown that adaptation to periodic hypoxia results in improvement of general condition of patients who exhibited a decline in blood pressure, minute blood volume, serum sodium concentrations as well as
A link between exaggerated chemoreceptor sensitivity and hypertension has been documented in the spontaneously hypertensive rat (SHR) but has also been questioned when comparisons with normotensive strains other than the Wistar Kyoto (WKY) rat are made. To further evaluate the link between
Systemic hypertension is one of the most prevalent cardiovascular diseases. Sleep-disordered breathing (SDB) with recurrent apnea is a major risk factor for developing essential hypertension. Chronic intermittent hypoxia (CIH) is a hallmark manifestation of recurrent apnea. Rodent models patterned
The response to intermittent normobaric hypoxia (INH) created in breathing gas hypoxia mixture (10% oxygen, 90% nitrogen) was evaluated in 123 patients with essential hypertension stage I and II. Hypoxia adaptation effects on central hemodynamics, physical performance, kinetics of oxygen exchange
BACKGROUND
African Americans develop hypertension earlier with more target manifestations than whites despite having a higher glomerular filtration rate (GFR) for any level of serum creatinine. STUDY DESIGN & PARTICIPANTS: This study tested the hypothesis that increased GFR and sodium reabsorption