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eudesmane sesquiterpene/necrosis
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New eudesmane sesquiterpenes from Alpinia oxyphylla and determination of their inhibitory effects on microglia.
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The fruits of Alpinia oxyphylla are used as healthcare products for the protection on neurons and prevention of dementia. Two new noreudesmane sesquiterpenoids, (5R,7S,10S)-5-hydroxy-13-noreudesma-3-en-2,11-dione (1) and (10R)-13-noreudesma-4,6-dien-3,11-dione (2), and a new eudesmane
A prenylbisabolane with NF-kappaB inhibiting properties from Cascarilla (Croton eluteria).
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Investigation of the bark of Croton eluteria Bennett for biologically active compounds has led to the isolation of the new prenylbisabolane 3, whose structure was assessed by spectroscopic methods. The corresponding known enone 4 and the eudesmane sesquiterpene 2 were also obtained. Compound 3
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