fissure in ano/nausea

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A randomized trial of oral vs. topical diltiazem for chronic anal fissures.

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BACKGROUND Chemical sphincterotomy has proved effective in treating chronic anal fissure. Glyceryl trinitrate is the most widely used agent, and topical 0.2 percent glyceryl trinitrate ointment heals up to two thirds of chronic anal fissures. Unfortunately, however, many patients experience

Surgical treatment of anal fissures under local anesthesia.

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OBJECTIVE To evaluate lateral sphincterotomy under a mixture of local anesthesia versus general anesthesia in the treatment of anal fissures. METHODS A randomized clinical trial of 62 consecutive patients requiring lateral sphincterotomy was carried out at Princess Haya Al-Hussein Hospital in

Nicorandil-associated ulcerations.

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This leading article refers to the paper by Abdelrazeq AS, Owen C, Smith L, McAdam JG, Pearson HJ, Leveson SH. Nicorandil-associated para-stomal ulceration: case series Eur J Gastroenterol Hepatol 2006; 18:1293-1295. We apologise to all concerned for the dissociation between the two papers, which

A bulking agent may lead to adrenal insufficiency crisis: a case report.

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Adrenal insufficiency is a life-threatening disorder which must be treated with glucocorticoid replacement and needs permanent dose adjustment during patient's different somatic situations. Insufficient glucocorticoid doses result in adrenal crisis and must be treated with intravenous

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