glutamate decarboxylase/dental caries

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Increasing thermal stability and catalytic activity of glutamate decarboxylase in E. coli: An in silico study.

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Glutamate decarboxylase (GAD) is an enzyme that converts l-glutamate to gamma amino butyric acid (GABA) that is a widely used drug to treat mental disorders like Alzheimer's disease. In this study for the first time point mutation was performed virtually in the active site of the E. coli GAD in

Synaptic input and local output of dopaminergic neurons in grafts that functionally reinnervate the host neostriatum.

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In adult rats with a unilateral 6-hydroxy-dopamine-induced lesion of the nigrostriatal dopamine pathway, grafts of embryonic ventral mesencephalon can establish extensive efferent connections with the previously denervated host neostriatum and can compensate for motor and sensorimotor asymmetries

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Herbal & Natural Medicine

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