glycyrrhizic acid/breast neoplasms

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Glycyrrhizic acid induces human MDA-MB-231 breast cancer cell death and autophagy via the ROS-mitochondrial pathway.

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Glycyrrhizic acid (GA), the main component of licorice root extracts, has been shown to suppress cell proliferation and induce apoptosis in various types of cancers. However, the molecular mechanism of its anticancer activity remains poorly understood and warrants further investigation. MDA-MB‑231

[Content of progesterone, glucocorticoid and glycyrrhizic acid receptors in normal and tumoral human breast tissue].

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Progesterone and glucocorticoid receptor levels were assayed in breast tumor. The progesterone levels in tumor were 1.2-2.5 times those in normal tissue sampled from the same patients. The binding of glycyrrhizic acid (GA) to cytoplasmic proteins (GA "receptor" levels) was studied using procedures

Modulation of intestinal microbiota by glycyrrhizic acid prevents high-fat diet-enhanced pre-metastatic niche formation and metastasis.

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High-fat diet (HFD) promotes lung pre-metastatic niche formation and metastasis. Thus, there is an urgent need to identify the underlying mechanisms and develop strategies to overcome them. Here we demonstrate that glycyrrhizic acid (GA) prevents HFD-enhanced pre-metastatic niche formation and

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