guaianolide/nicotiana

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Kauniolide synthase is a P450 with unusual hydroxylation and cyclization-elimination activity.

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Guaianolides are an important class of sesquiterpene lactones with unique biological and pharmaceutical properties. They have been postulated to be derived from germacranolides, but for years no progress has been made in the elucidation of their biosynthesis that requires an unknown cyclization

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Herbal & Natural Medicine

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