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guettarda speciosa/chloroform

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A new iridoid from Guettarda grazielae M.R.V. Barbosa (Rubiaceae).

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Chromatographic fractionation of the chloroform extracts from the stem bark and stems of Guettarda grazielae resulted in the isolation of a new iridoid (guettardodiol, 1) and the secoiridoid sarracenin (2), described for the first time in this genus. The structural elucidation of these compounds was

Cytotoxic activity of Guettarda pohliana Müll. Arg. (Rubiaceae).

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The cytotoxic activity of crude extracts and their fractions from leaves and roots of G. pohliana was assessed against nine human cancer cell lines: melanoma (UACC-62), breast (MCF-7), breast expressing the multidrug resistance phenotype (NCI-ADR), lung (NCI-460), prostate (PCO-3), kidney (786-0),
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