non surgical periodontal therapy will be given to study subjects which will be selected by randomization from total study sample. at the end of study, serum albumin levels of both study and control groups will be compared.

End Stage Renal Failure on Dialysis

Periodontitis

dental scaling and root planing of full mouth will be done

non-surgical periodontal therapy

Shaikh Zayed Medical Complex

Effect of Non-Surgical Periodontal Therapy on Serum Albumin Levels of Patients on Maintenance Hemodialysis Therapy,

Effect of Non-Surgical Periodontal Therapy on Serum Albumin Levels of Patients on Maintenance Hemodialysis Therapy, A Randomized Control Trial

serum albumin levels are considered to be strong predictor of death in dialysis patients. in this trial we want to see the effect of non surgical periodontal therapy on serum albumin levels of patients on maintenance dialysis therapy

Dr Arsalan Wahid

Principal Investigator

University of the Punjab

Patients receive once a day trientine
Once a day Trientine: Trientine at a dosage of ~15 mg/kg rounded upwards to the nearest 250 or 300 mg in a single daily dosage. The entire daily dosage will be taken at once in the AM an hour before any meal. Duration of the study is 1 year.

Once a Day Trientine

Sex: Female, Male

Ethnicity (NIH/OMB)

Race (NIH/OMB)

Region of Enrollment

Treatment for Wilson's Disease prior to study entry

Prior Treatment

The International Normalized Ratio (INR) is a standard way to describe the time it takes for blood to clot; an INR range of 0.8 to 1.2 is considered normal for a healthy person who is not using oral anticoagulant therapy

Albumin

Cu Serum

Cu Urine

Zn Urine

Overall Study

Dr. Schilsky

Wilson Disease

Trientine at a dosage of ~15 mg/kg rounded upwards to the nearest 250 or 300 mg in a single daily dosage. The entire daily dosage will be taken at once in the AM an hour before any meal. Duration of the study is 1 year.

Once a day Trientine

Yale University

Single Daily Dosage of Trientine for Maintenance Treatment for Wilson Disease

Michael Schilsky

Assoc Prof Int Med Digestive Disease and Surg Transplant

Bausch Health Americas, Inc.

Wilson's Disease

1.000.000(one million) cells/kg, IV (1/2 of dose in the Peripheral vein and 1/2 of dose into the right hepatic artery)

allogeneic mesenchymal stem cell transplantation

Department of Gastroenterology; Gulhane Military Medical Academy

Efficacy of Invitro Expanded Bone Marrow Derived Allogeneic Mesenchymal Stem Cell Transplantation Via Portal Vein or Hepatic Artery or Peripheral Vein in Patients With Wilson Cirrhosis

all patients will be transplanted bone marrow derived mesenchymal stem cells belonging to the opposite sex in order to genetically determine the mature hepatocyte

hepatolenticular degeneration/albumin

Effect of Non-Surgical Periodontal Therapy on Serum Albumin Levels of Patients on Maintenance Hemodialysis Therapy,

Single Daily Dosage of Trientine for Maintenance Treatment for Wilson Disease

Efficacy of Invitro Expanded Bone Marrow Derived Allogeneic Mesenchymal Stem Cell Transplantation Via Portal Vein or Hepatic Artery or Peripheral Vein in Patients With Wilson Cirrhosis

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