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hydrops fetalis/dolichos
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Glomerular and proximal tubule cysts as early manifestations of Pkd1 deletion.
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BACKGROUND
The homozygous deletion of Pkd1 in the mouse results in embryonic lethality with renal cysts and hydrops fetalis, but there is no precise data on the segmental origin of cysts and potential changes associated with polyhydramnios.
METHODS
We used Pkd1-null mice to investigate cystogenesis
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