infectious mononucleosis/protease

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Specific release of heterogenetic mononucleosis receptor by influenza viruses, receptor destroying enzyme and plant proteases.

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Immunochemical studies of infectious mononucleosis. IV. Effect of proteases on the glycoprotein of horse erythrocytes.

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Kinetics, inhibition and oligomerization of Epstein-Barr virus protease.

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Epstein-Barr virus (EBV) is an omnipresent human virus causing infectious mononucleosis and EBV associated cancers. Its protease is a possible target for antiviral therapy. We studied its dimerization and enzyme kinetics with two enzyme assays based either on the release of paranitroaniline or

B cell-derived circulating granzyme B is a feature of acute infectious mononucleosis.

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Granzyme B (GzmB) is a serine protease best known for inducing target cell apoptosis when released by cytotoxic T lymphocytes (CTLs) or natural killer cells with pore-forming perforin. As a result, GzmB detected in the serum of virus-infected individuals has typically been attributed to these

[Regulation and evasion of host immune responses by Epstein-Barr virus].

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Epstein-Barr virus (EBV) is the first identified human oncogenic DNA virus in the gamma-herpesvirus family. EBV triggers a cascade events of innate immune responses through Toll-like receptor signaling including the production of type I interferons and the activation of functional autophagy.

Outcome of liver disease associated with alpha 1 antitrypsin deficiency (PiZ). Implications for genetic counselling and antenatal diagnosis.

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We reviewed the hepatic features in 136 children with alpha 1 antitrypsin deficiency (PiZ). Eighty two were studied prospectively, 74 of whom had chronic liver disease. Sixty seven children with liver disease presented in the first four months of life, four were older infants and children with

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