Subjects were randomly allocated to a group and entered a 4-week "washout period" during which no gum was chewed, followed by a 3-week treatment period (treatment period 1) during which Group A used Xylitol gum.(2 gum pieces, 3 times daily after meals for 6 minutes).Then underwent another 4-week washout period before entering treatment period 2 during which Group A used Gum Sorbitol

Subjects were randomly allocated to a group and entered a 4-week "washout period" during which no gum was chewed, followed by a 3-week treatment period (treatment period 1) during which Group B used sorbitol gum. Group B used Gum Sorbitol (2 gum pieces, 3 times daily after meals for 6 minutes).Then underwent another 4-week washout period before entering treatment period 2 during which Group B used Gum xylitol

Human Microbiome

Xylitol gum contains 70% xylitol in addition to gum base, natural flavors, soy lecithin, gum arabic, titanium dioxide, carnuba wax. Sorbitol gum was similar except that xylitol was replaced by 63% sorbitol and 2% maltitol and aspartame was included.

Xylitol then Sorbitol gum

Sorbitol gum was similar except that xylitol was replaced by 63% sorbitol and 2% maltitol and aspartame was included. Xylitol gum contains 70% xylitol in addition to gum base, natural flavors, soy lecithin, gum arabic, titanium dioxide, carnuba wax.

Sorbitol then Xylitol gum

Xylitol and Sorbitol Effects on the Oral Microbiome

Xylitol and Sorbitol Effects on the Microbiome of Saliva and Plaque

Profile microbial communities of saliva and plaque based high-throughput sequencing of the 16S rRNA gene.

Reisha Rafeek

Senior Lecturer

The University of The West Indies

J. Craig Venter Institute

For photodynamic therapy will be used an equipment developed for this project with emission of red LED (660nm) and tip of 2.84 cm² .One session of the Chimiolux® photosensitizing aPDT will be performed, at a concentration of 0.005%, to be applied enough to cover the middle third and back of the tongue for 2 minutes for incubation. Four points will be irradiated with a distance of 1cm between the points, considering the scattering halo and the effectiveness of aPDT. The LED apparatus will be previously calibrated with wavelength 660 nm, with energy of 72 J, power of 800 mW for 90 seconds per point, creep of 282mW / cm².

Tongue scraper 10 times in the tongue, from the back to the front.

Tongue scraper 10 times in the tongue, from the back to the front. For aPDT will be used an equipment developed for this project with emission of red LED (660nm) and tip of 2.84 cm² . One session of the Chimiolux® photosensitizing aPDT will be performed, at a concentration of 0.005%, to be applied enough to cover the middle third and back of the tongue for 2 minutes for incubation. Four points will be irradiated with a distance of 1cm between the points. Based on previous studies carried out with the aPDT for the treatment of halitosis the apparatus will be previously calibrated with wavelength 660 nm, with energy of 72 J, power of 800 mW for 90 seconds per point, creep of 282mW / cm².

Halitosis

aPDT with methylene blue and red led irradiation.

photodynamic therapy

Tongue scraper 10 times from de back to the top.

Tongue scraper

University of Nove de Julho

Photodynamic Therapy With Red Leds in Microorganisms Related to Halitosis

Action of Antimicrobial Photodynamic Therapy With Red Leds in Microorganisms Related to Halitose: Clinical Controlled and Randomized Trial

If halitosis reduces in patients after treatment

If aPDT reduces the microorganism related to halitosis after treatment

Ana Carolina Costa da Mota

Clinical Professor

A controlled, quantitative cross-sectional clinical study.

isoamyl alcohol/dental caries

Xylitol and Sorbitol Effects on the Oral Microbiome

Photodynamic Therapy With Red Leds in Microorganisms Related to Halitosis

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