isopropanol/lafyèv

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Hemorrhagic gastritis from topical isopropanol exposure.

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OBJECTIVE To report the occurrence of hemorrhagic gastritis after topical isopropanol application in an infant. METHODS A 2-year-old Hispanic boy developed coffee-ground emesis during emergency department evaluation for lethargy and fever. After an initial inconclusive workup for sepsis, further

Isopropanol ingestion: interpretation of blood concentrations and clinical findings.

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We evaluated blood concentrations and clinical findings in 17 cases of isopropanol (IPROH) ingestion seen over a 8.5 year period at our institution. Eight ingestions involved IPROH alone ("pure") while the remainder involved at least ethanol in addition to IPROH ("mixed"). Fourteen patients had a

Targeted protein degradation by Salmonella under phagosome-mimicking culture conditions investigated using comparative peptidomics.

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The pathogen Salmonella enterica is known to cause both food poisoning and typhoid fever. Because of the emergence of antibiotic-resistant isolates and the threat of bioterrorism (e.g. contamination of the food supply), there is a growing need to study this bacterium. In this investigation,

Severe and Progressive Cellulitis Caused by Serratia marcescens Following a Dog Scratch.

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Soft tissue infections occur in over 30% of patients with chemotherapy-induced neutropenia. Gram-positive bacterial infections predominate early in neutropenia, and likelihood of infection by resistant bacteria and fungi increases with prolonged neutropenia. Prior infections and exposures influence

Molecular serotyping of dengue viruses in field-caught Aedes mosquitos by in-house RNA extraction/RT-PCR reagent kits.

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We developed in-house RNA extraction and RT-PCR reagent kits for the molecular serotyping of dengue viruses in field-caught Aedes mosquitos. Mosquitos that showed positive results by ELISA or IFA were selected for the identification of dengue viruses in order to predict the distribution of the four

Tumor necrosis factor activity in the circulation of horses given endotoxin.

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Serum and plasma from horses injected with endotoxin was examined for cytotoxic activity. Each of the cell lines, L929 and WEHI 164 clone 13, was sensitive to the cytotoxic effects of equine serum; however, a precipitation artifact caused by the use of isopropanol in the WEHI assay limited the use

Unstable hemoglobins: influence of environment on phenotypic expression of a genetic disorder.

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Unstable hemoglobins account for approximately one fifth of the abnormal hemoglobins identified to date. Clinical expression ranges from a continuing and severe hemolytic anemia which may or may not be abated by splenectomy to a compensated hemolytic state with exacerbations of hemolysis after

Re-evaluation of the culture condition of polymorphonuclear cells for the study of apoptosis induction.

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The culture conditions of human peripheral blood polymorphonuclear leukocytes (PMN) in the study of apoptosis induction were re-evaluated. The changes in the relative viable cell number of PMNs after tumor necrosis factor (TNF) treatment were colorimetrically investigated using a cell counting kit.

A comparison of the absorption and metabolism of isopropyl alcohol by oral, dermal and inhalation routes.

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The admission of a child with an almost lethal level of isopropyl (alcohol 380 mg/dl) after sponge bathing for fever, and questionable ingestion, prompted the present experiment in animals. Twelve rabbits (2-2.6 kg) were divided into 4 groups of 3 each. Groups 1 and 2 were given isopropyl alcohol, 2

Thermal analysis of CHL V79 cells using differential scanning calorimetry: implications for hyperthermic cell killing and the heat shock response.

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Differential scanning calorimetry (DSC) was used to assay thermal transitions that might be responsible for cell death and other responses to hyperthermia or heat shock, such as induction of heat shock proteins (HSP), in whole Chinese hamster lung V79 cells. Seven distinct peaks, six of which are

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