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Argentina: seizure of universities leaves intellectual casualties.

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Anticonvulsant Activity of Extracts of Plectranthus barbatus Leaves in Mice.

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Plectranthus barbatus is a medicinal plant used to treat a wide range of disorders including seizure. However, the anticonvulsant activity of this plant has not been studied in depth. We therefore sought to evaluate the anticonvulsant activity of a hydroalcoholic extract of P. barbatus leaves on

Effects of the Aqueous Extract of Anethum graveolens Leaves on Seizure Induced by Pentylenetetrazole in Mice.

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BACKGROUND In this study, the aqueous extract of Anethum graveolens (dill) leaves was studied for its effects on treating convulsions and epilepsy, by using a pentylenetetrazole (PTZ) kindling model. The evaluated plant has a traditional medical reputation for profound anticonvulsant activities,

Anticonvulsant effect of ethanolic extract of Cyperus articulatus L. leaves on pentylenetetrazol induced seizure in mice.

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Cyperus articulatus (CA) rhizomes have demonstrated different properties on nervous system. However, the leaves still have not studied to treat epilepsy. The aim of this study was to determine the effect of CA ethanolic extract on pentylenetetrazol (PTZ) induced seizures in mice as well as measuring

Antiepileptic potential of flavonoids fraction from the leaves of Anisomeles malabarica.

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BACKGROUND The plant Chodara (Anisomeles malabarica R.Br. Family: Lamiaceae) has numerous therapeutic utilities in folk medicine. OBJECTIVE To isolate and evaluate the anti-epileptic potential of fractions from the ethyl acetate extract (EAE) of Anisomeles malabarica leaves. METHODS The EA extract

Anxiolytic and anticonvulsive activity of Sesbania grandiflora leaves in experimental animals.

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Various parts of Sesbania grandiflora have been used in the Indian system of medicine, in particular, the leaves of S. grandiflora are used in Ayurveda for the treatment of epileptic fits. In the present study we have evaluated the anticonvulsive activity of S. grandiflora leaves using a variety of

Behavioral studies on alkaloids extracted from the leaves of Hunteria zeylanica.

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The effects of a crude methanol extract, butanol- and chloroform-fractions, and a pure compound, corymine, extracted from the leaves of H. zeylanica on locomotor activity and rearing, pentobarbital-induced sleep, and drug-induced convulsions were studied in mice. The methanol extract

Antiasthmatic activity of the methanol extract of leaves of Passiflora incarnata.

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The methanol extract of the leaves of P. incarnata was evaluated for its antiasthmatic effects against acetylcholine chloride (Ach)-induced-bronchospasm in guinea-pigs at doses of 50, 100 and 200 mg/kg. Using a 7-day treatment regimen, significant prevention of dyspnoea-related-convulsions was noted

Is monofluoracetic acid the active neurotoxic principle in Palicourea marcgravii (St. Hill) leaves?

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Acute intoxication of rats with the crude extract of Palicourea marcgravii (PM) and with monofluoracetic acid (MFA) solutions was compared since it has been reported that PM leaves contain monofluoracetates (455 micrograms/g air-dried material). The neurotoxic signs produced by oral administration

Investigations into the toxicity of the leaves of Erythrophleum guineense Don. in sheep.

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An investigation was carried out on the toxicity of the leaves of Erythrophleum guineense Don. in sheep. Four groups of two animals each were fed 8, 2, 0.5 and 0.25 g/kg/day, respectively, of dried ground leaves of E guineense through a stomach tube. Two animals served as controls and received 8

Studies on neuropharmacological profile of ethanol extract of Moringa oleifera leaves in mice.

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BACKGROUND Moringa oleifera (family Moringaceae), commonly called Horseradish or tree of life, is traditionally used for the treatment of epilepsy and neurologic conditions. OBJECTIVE The objective of this study is to investigate the neurobehavioural and anticonvulsant properties of the ethanol

Anticonvulsant properties and bio-guided isolation of palmitone from leaves of Annona diversifolia.

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The activity-guided fractionation of the ethanol extract of leaves of Annona diversifolia Saff., led to the isolation of palmitone (16-hentriacontanone) as the only anticonvulsant active compound. This aliphatic ketone was highly effective to diminish pentylenetetrazole (PTZ)-induced clonic-tonic

Evidence of the mechanism of action of Erythrina velutina Willd (Fabaceae) leaves aqueous extract.

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BACKGROUND Erythrina velutina is traditionally used for sleepiness, convulsions and nervous system excitation in Brazil. Although central effects have been reported for Erythrina velutina, little is known about its mechanism of action. OBJECTIVE To investigate the pharmacological evidences of

CNS depressant and anticonvulsant activities of the alcoholic extract of leaves of Ziziyphus nummularia.

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BACKGROUND Ziziyphus nummularia (family: Rhamnaceae) is a xerophyte, grows in the grazing lands of the Thar Desert of Rajasthan. Ziziyphus nummularia (ZN) is used as sedative in ethnomedicine. The objective of this study is to investigate the anticonvulsant, anxiolytic and sedative activities of the

Neuropharmacological effects of an ethanol extract of the Magnolia dealbata Zucc. leaves in mice.

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Magnolia dealbata Zucc. is considered to have tranquilizer and anticonvulsant properties in Mexican traditional medicine. In the present study we report the effects of a crude extract of Magnolia dealbata (30, 100 and 300 mg/kg) on mouse central nervous system (CNS). Pharmacological effects were

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