lupinus hintonii/hypersensitivity

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Cross-allergenicity of peanut and lupine: the risk of lupine allergy in patients allergic to peanuts.

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BACKGROUND Peanut allergy is common, but cross-allergy between legumes is rare. Proteins from Lupinus albus are increasingly eaten in the form of seeds or additives to wheat flour. The risk of cross-allergenicity is still insufficiently known. OBJECTIVE We sought to study the risk of cross-allergy

Prick by prick induced anaphylaxis in a patient with peanuts and lupine allergy: awareness of risks and role of component resolved diagnosis.

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A case of anaphylaxis is reported in the course of a prick by prick with Lupinus albus and roasted peanut in a 20-year-old woman. We focused on some main topics. First of all it seems important to underscore the potential risks connected to the practice of the prick-by-prick with fresh foods in

[Risk of serious acute asthma due to lupine flour associated with peanut allergy].

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Lupine flour (lupinus albus), recently authorized in France in human food, cross-reacts with peanuts. We report a case of acute asthma in a patient with allergy to peanuts. METHODS This patient has a severe allergy to peanuts, presenting as acute asthma. Skin prick-tests to raw and cooked lupine

Lupine-induced anaphylaxis in a child without known food allergy.

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BACKGROUND Lupine allergy is caused by ingestion of the flour of a plant called Lupinus albus, a member of the Leguminosae family. Lupine allergy has been described in adult patients previously known to have peanut allergy (cross-reactivity). OBJECTIVE To describe the first case of an anaphylactic

A plant-based allergy vaccine suppresses experimental asthma via an IFN-gamma and CD4+CD45RBlow T cell-dependent mechanism.

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Allergic asthma is currently considered a chronic airway inflammatory disorder associated with the presence of activated CD4(+) Th2-type lymphocytes, eosinophils, and mast cells. Interestingly, therapeutic strategies based on immune deviation and suppression have been shown to successfully attenuate

A mouse model of lupin allergy.

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BACKGROUND Lupin has been introduced as a new food ingredient in an increasing number of European countries, resulting in reports of allergic reactions mostly due to cross-reactions in peanut-allergic individuals. Some cases of primary lupin allergy have also been reported. OBJECTIVE The aim of our

Cross-allergic reactions to legumes in lupin and fenugreek-sensitized mice.

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Several legumes may induce allergy, and there is extensive serological cross-reactivity among legumes. This cross-reactivity has traditionally been regarded to have limited clinical relevance. However, the introduction of novel legumes to Western countries may have changed this pattern, and in some

Lupin sensitization and clinical allergy in food allergic children in Norway.

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OBJECTIVE The aim of the present pilot study was to investigate to what extent children in Norway sensitized to lupin had clinical lupin allergy, and to compare sensitization to lupin with sensitization to other legumes. METHODS Thirty-five children with food allergy referred to a national referral

Characterization of IgE binding to lupin, peanut and almond with sera from lupin-allergic patients.

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BACKGROUND The increasing number of applications of sweet lupins in food is paralleled by an increase in immunoglobulin E (IgE)-mediated allergic reactions to lupin proteins. In particular, lupin allergy seems to appear in patients with an existing peanut allergy. In the present study, IgE-binding

Lupin allergy in peanut-allergic children and teenagers.

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BACKGROUND Lupin has now been introduced into food production in the UK. There is a concern that, on account of cross-reactivity, peanut-allergic children are at high risk for lupin allergy. OBJECTIVE To investigate the prevalence of lupin sensitization and allergy in children with peanut allergy

Lupin allergy and lupin sensitization among patients with suspected food allergy.

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BACKGROUND Lupin, a legume with good nutritional value, is used in food production today, most often in bakery products. Lupin sensitization is often seen among patients with reactions to legumes, but the number of reports describing lupin anaphylaxis is also increasing. OBJECTIVE To investigate the

Variably severe systemic allergic reactions after consuming foods with unlabelled lupin flour: a case series.

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BACKGROUND Lupin allergy remains a significant cause of food-induced allergic reactivity and anaphylaxis. Previous work suggests a strong association with legume allergy and peanut allergy in particular. Both doctors and the public have little awareness of lupin as an allergen. METHODS Case 1 was a

The prevalence of sensitization to lupin flour in France and Belgium: a prospective study in 5,366 patients, by the Allergy Vigilance Network.

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OBJECTIVE To determine the prevalence of sensitization to lupin flour in patients consulting allergists, in order to evaluate the risk of primary and secondary allergies to lupin. METHODS A prospective study carried out by members of the Allergy Vigilance Network, using prick-tests with a commercial

Lupin allergy: a hidden killer at home, a menace at work; occupational disease due to lupin allergy.

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The products of the flowering plant, lupin, are increasingly used as a human food product, particularly in baking. Occupational sensitization to lupin with occupational rhinitis, conjunctivitis and asthma was first described in 2001, and confirmed in a larger cross-sectional study in a food

Characterization of the sensitization profile to lupin in peanut-allergic children and assessment of cross-reactivity risk.

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BACKGROUND Case reports of allergy to lupin, due to primary sensitization or cross-reactions with other legumes, are increasing as a consequence of the augmented use of lupin flour in bakery, pasta formulations and other food items. The main allergens that have been associated with the sensitization

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