maytenus evonymoides/breast neoplasms

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Imines and lactones derived from friedelanes and their cytotoxic activity.

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Friedelan-3-one (1) and friedelane-3,16-dione (2) isolated from leaves and branches of Maytenus robusta Reissek were subjected to structural modifications via nucleophilic addition to the carbonyl group and Baeyer-Villiger oxidation in order to synthesize potential cytotoxic compounds. The oximes

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