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microphthalmos/cannabis
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Endocannabinoids stimulate human melanogenesis via type-1 cannabinoid receptor.
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We show that a fully functional endocannabinoid system is present in primary human melanocytes (normal human epidermal melanocyte cells), including anandamide (AEA), 2-arachidonoylglycerol, the respective target receptors (CB(1), CB(2), and TRPV1), and their metabolic enzymes. We also show that at
Dose-dependent teratogenicity of the synthetic cannabinoid CP-55,940 in mice.
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Potent synthetic cannabinoids (SCBs) are illegally distributed drugs of abuse that are frequently consumed in spite of their adverse consequences. This study was designed to determine if the toxicity observed in adults also extends to the prenatal period by examining the developmental
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