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miliusa tomentosa/alkaloid

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Two new alkaloids from Miliusa cuneata.

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Two new isoquinoline alkaloids, 2,10-dimethoxy-3,11-dihydroxy-5,6-dihydroprotoberberine (1) and 1,9-dihydroxy-2,11 -dimethoxy-4,5-dihydro-7-oxoaporphine (2), together with thirteen known alkaloids, were isolated from the ethanolic extracts of the stem and leaves of Miliusa cuneata (Graib). Their

Antimalarial Oxoprotoberberine Alkaloids from the Leaves of Miliusa cuneata.

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Five new oxoprotoberberine alkaloids, miliusacunines A-E (1-5), along with nine known compounds, 6-14, were isolated from an acetone extract of the leaves and twigs of Miliusa cuneata. Their structures were elucidated by spectroscopic analysis. All isolated compounds were evaluated for their
The oxoaporphine alkaloids oxophoebine [1] and liriodenine [2] have been isolated from Xylopia aethiopica (Annonaceae). Both showed selective toxicity against DNA repair and recombination deficient mutants of the yeast Saccharomyces cerevisae. Three related but inactive compounds, oxoglaucine [3],

Genus Miliusa: A Review of Phytochemistry and Pharmacology.

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Background
Genus Miliusa (family Annonaceae), widely distributed in mainland Asia and Australia to New Guinea, has been employed in both traditional herbal uses and pharmacological medicines. Original research articles related to this genus are now available, but
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