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Incorporation of sciadonic acid into cellular phospholipids reduces pro-inflammatory mediators in murine macrophages through NF-κB and MAPK signaling pathways.

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Sciadonic acid (SCA; Δ5,11,14-20:3), a non-methylene-interrupted polyunsaturated fatty acid (NMIFA), can substitute for arachidonic acid (AA) and reduce prostaglandin E2 (PGE2) synthesis in macrophages. However, little is known about how SCA exerts its anti-inflammatory effects. The objectives of

Cytokine induction by LVAD in the canine kidney.

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BACKGROUND The outcome of left ventricular assist device (LVAD) support is reported to be associated with proinflammatory cytokines. We investigated the effect of LVAD support on renal function and the resultant cytokine induction. METHODS A prospective experimental study was performed using 15

Osteosynthesis of femoral-neck nonunion with angle blade plate and autogenous fibular graft.

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OBJECTIVE Revision internal fixation for femoral-neck nonunion is a challenging procedure. Treatment options are osteotomy, osteosynthesis using various implants and grafting techniques (muscle pedicle, vascularised or nonvascularised fibular graft) or arthroplasty. The objective of this article is

Novel lumen-apposing metal stent for the drainage of pancreatic fluid collections: An Italian multicentre experience.

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UNASSIGNED Endoscopic ultrasound (EUS)-guided drainage is the procedure of choice for pancreatic fluid collection (PFC) management. Recently developed lumen-apposing fully covered self-expandable metal stents (LAMSs) may facilitate drainage, especially of necrotic and complex PFCs. UNASSIGNED To

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