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naringenin/kansè
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Application of naringenin and naringin in tumor radiotherapy
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is the national phase entry of International Application No. PCT/CN2016/096711, filed on Aug. 25, 2016, which is based upon and claims priority to Chinese Patent Application No. CN201510404716.2, filed on Jul. 10, 2015, the entire contents of
Compositions and methods for selectively inhibiting intestinal carboxylesterase 2 enzyme activity
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BACKGROUND
Camptothecin (CPT)-derived drugs, such as irinotecan (CPT-11), are typically used for treating solid brain, colon, and lung tumors, as well as for treating refractory forms of leukemia and lymphoma. See Pommier Nat. Rev. Cancer, 6(10):789 802.
The antineoplastic efficacy of CPT-11 is
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