necrobiotic xanthogranuloma/amyloid

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[Necrobiotic xanthogranuloma with skin and liver amyloidosis].

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BACKGROUND Necrobiotic xanthogranuloma is a largely unknown disease. Both the frequency of this disease and the involvement of internal organs have clearly been underestimated until now. METHODS A patient was admitted because of ulcerating, xanthomatous, subcutaneous nodules, scleritis and

Necrobiotic xanthogranuloma with paraproteinemia: an evolving presentation.

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Necrobiotic xanthogranuloma with paraproteinemia is a progressive and destructive process that is often confused both clinically and histologically with other granulomatous and xanthomatous entities. It was first described by Kossard and Winkelmann in 1980. Prior to this, the entity was reported

Case of multiple myeloma associated with extramedullary cutaneous plasmacytoma and pyoderma gangrenosum.

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A variety of cutaneous manifestations has been described in multiple myeloma including extramedullary cutaneous plasmacytomas, cutaneous amyloidosis, pyoderma gangrenosum, leukocytoclastic vasculitis, necrobiotic xanthogranuloma, scleromyxedema, Sweet's syndrome, subcorneal pustular dermatosis,

Multisystem diseases affecting the skin and eye.

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There exist a wide variety of multisystem diseases that can affect both the eyes and skin. The skin and eyes may be the initial sites affected, leading to a new diagnosis of a systemic illness, or severe skin and eye involvement can drive treatment for patients with multisystem disease. It is

Xanthoma-like Skin Changes in an Elderly Woman with a Normal Lipid Profile.

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Dear Editor, An 83-year-old woman developed yellow-brownish infiltrates, nodules, and tumors mimicking xanthomas, mostly involving the periorbital and chest area within three months (Figure 1). She had no abnormalities in serum cholesterol or triglycerides levels. A detailed laboratory analysis

[Skin disorders associated with monoclonal gammopathies].

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A monoclonal gammopathy is a condition in which a monoclonal immunoglobulin (M-protein, formerly known as paraprotein) produced by a clonal proliferation of plasma cells is present in the blood. The spectrum of monoclonal gammopathies includes monoclonal gammopathy of uncertain significance (MGUS),

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