necrolytic migratory erythema/atrophy

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Ultrastructural studies of necrolytic migratory erythema.

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Necrolytic migratory erythema is a disorder highly suggestive of glucagonoma syndrome. We carried out histologic and electron microscopic studies of the skin lesions in a 57-year-old woman with the glucagonoma syndrome. Light microscopic studies revealed hyperkeratosis, parakeratosis, formation of

[Necrolytic migratory erythema: glucagonoma syndrome. Clinical and histological aspects].

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The author reviews a personal and other reported cases of necrolytic migratory erythema, a useful marker of glucagon-secreting islet cell tumours of the pancreas. The lesions extend and migrate as the centres form either a bulla or a parakeratotic crust. The eruption involves particularly the body

Retrobulbar neuritis as the first sign of the glucagonoma syndrome.

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A 63-year-old man with a metastasising pancreatic glucagonoma is described, who presented with progressive deterioration of vision and bilateral central scotomata as the first symptom. This patient was treated with dacarbazine (DTIC) 250 mg/m2 IV daily for five consecutive days at 4-week intervals.

Vesicular and ulcerative dermatopathy resembling superficial necrolytic dermatitis in captive black rhinoceroses (Diceros bicornis).

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The histopathology, clinical presentation, and epidemiology of a cutaneous and oral mucosal disease affecting 40 black rhinoceroses (Diceros bicornis) at 21 zoological parks (50% of the captive US population) were investigated. Twenty-seven biopsies were examined from recent lesions, and clinical

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